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转基因作物伤害动物内脏(论文全文)(18)

Based on Table , all the parameters statistically significant different between GM corn fed rats and corresponding controls are represented by their crude means ± SEM in exact corresponding units. The differences were always p < 0.05 or < 0.01 compared to controls according to one or two asterisks in Table . The symbol (p) means that the difference is significant only in a parametric test. The controls are submitted to substantially equivalent isogenic maize with the same diet composition, with all usual conditions exactly identical (genetic, temperature, light, space of caging, water and others). The time of exposure (weeks 5 and 14 corresponding, respectively, to 4 and 13 weeks of GMO diet), the sexes (males: m, females: f), and the dose (11 or 33% of GM maize in the equilibrated diet) are indicated.

Parameters

Unit

Week

Sex

Dose (%)

Control

GMO


mean ± sem

mean ± sem


                           

BONE MARROW

                         

Abs. lymphocytes

 

µL (X10E3)

 

14

 

f

 

33

 

6.01 ± 0.62

 

4.65 ± 0.24

 

Neutrophils

 

µL (X10E3)

 

14

 

m

 

33

 

17.51 ± 0.7

 

11.60 ± 0.89

 

Lymphocytes

 

%

 

14

 

m

 

33

 

74.41 ± 0.58

 

80.53 ± 1.06

 

Eosinophils (p)

 

%

 

5

 

m

 

11

 

1 ± 0.11

 

1.38 ± 0.11

 

Lar uni cell

 

%

 

5

 

f

 

11

 

1.23 ± 0.09

 

1.64 ± 0.11

 
                           

HEART

                         

Heart Wt

 

g

 

14

 

m

 

33

 

1.78 ± 0.04

 

1.98 ± 0.06

 

Heart % Body Wt

 

%

 

14

 

m

 

33

 

0.33 ± 0.01

 

0.36 ± 0.01

 

Heart % Brain Wt

 

%

 

14

 

m

 

33

 

80.18 ± 2.18

 

87.22 ± 2.47

 
                           

KIDNEY

                         

Urine Phosphorus

 

mg/dL

 

5

 

m

 

33

 

110.73 ± 8.66

 

185.38 ± 11.13

 

Urine Phosphorus

 

mg/dL

 

5

 

f

 

33

 

182.35 ± 15.4

 

254.08 ± 23.65

 

Urine Phosphorus

 

mg/dL

 

14

 

m

 

33

 

88.69 ± 19.86

 

174.77 ± 9.75

 

Urine sodium (p)

 

mmol/L

 

14

 

m

 

33

 

30 ± 4.11

 

43.2 ± 4.33

 

Urine potassium

 

mmol/L

 

14

 

m

 

33

 

166.72 ± 22.95

 

223.90 ± 12.02

 

Urine creat. clearance

 

mL/min/100 g/bw

 

5

 

m

 

33

 

0.59 ± 0.05

 

0.84 ± 0.06

 

Blood urea nitrogen

 

mg/dL

 

5

 

m

 

11

 

14.02 ± 0.61

 

12.10 ± 0.29

 

Blood urea nitrogen

 

mg/dL

 

5

 

m

 

33

 

14.84 ± 0.75

 

12.93 ± 0.47

 

Creatinine

 

mg/dL

 

5

 

m

 

11

 

0.32 ± 0.02

 

0.24 ± 0.02

 

Creatinine

 

mg/dL

 

5

 

m

 

33

 

0.31 ± 0.01

 

0.24 ± 0.02

 

Phosphorus

 

mg/dL

 

5

 

m

 

33

 

8.02 ± 0.15

 

7.48 ± 0.17

 

Potassium

 

mmol/L

 

14

 

f

 

33

 

7.30 ± 0.15

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